營養補給品對癌症患者有幫助

挪威研究報告指出，平時服用營養補給品的肺癌患者比沒有服用的生存機率較高。在國際癌症期刊上發表的研究結果表示，對肺癌患者來說,服用魚肝油營養補給品降低了44%的死亡率，而肺癌患者服用其他補給品則降低30%。這個研究顯示，癌症患者在診斷前口服營養補充品會有較高的生存率。

研究並指出服用營養補充品的益處甚至會延伸到對肺癌上。使用魚肝油還有其他的補充品提升了硬狀腫瘤(像乳癌和直腸癌)的生存機率。在68個挪威女性的自願者中，所服用的補充品經過統計後，服用最多的是鱈魚肝油，其次是綜合維他命還有礦物質補充品。在調整了吸煙的因素、年齡還有癌症階段後發現，硬狀腫瘤病人每日服用鱈魚肝油持續一年的死亡率降低了23%，而肺炎病人則是降低了44%。另外，在癌症病人中，每日攝取補充品則是降低了30%的死亡率，而偶爾服用則是降低了40%。

如果補充品是在診斷癌症後服用的話，研究結果有可能低估了補充品的成效。換句話說，如果需要長期的服用營養品來達到較好的生存效果的話，在診斷前服用會比之後來的有關聯。所以學者建議，在一些服用營養補充品很常見的國家，分析癌症患者的生存率(特別是肺癌患者)，應該要把營養補充品對患者的影響也列入評估。

Supplement users may have better cancer survival: Study

Lung cancer patients who were regular dietary supplement users prior to diagnosis may have better survival chances than non-users, says a new study from Norway.

Use of cod liver oil supplements was associated with a 44 per cent lower risk of death for lung cancer patients, while daily use of other dietary supplements was associated with a 30 per cent reduction in the risk of death among lung cancer patients, according to findings published in the International Journal of Cancer.

“This study has shown that in lung cancer patients taking dietary supplements before diagnosis was associated with better survival. Whether this is due to beneficial effects of supplements, or differences between supplement users and non-users cannot be determined,” wrote the researchers, led by Guri Skeie from the University of Tromso.

“More research is needed to understand the interplay between nutrients, whether in food or supplements and cancer survival.”

The study also indicated that the benefits of supplement use may even extend beyond lung cancer. The use of cod liver oil and other supplements was associated with improved survival statistics for people with any kind of solid tumour, including breast and colorectal cancer.

“Given that randomized controlled trials have demonstrated no effects or increased incidence of lung cancer in supplementation studies in well-nourished populations, our results may be somewhat surprising,” wrote the researchers. “However, these studies used pharmacological doses of specific nutrients, and cannot easily be compared with ours.”

Study details

Diet and supplement use was established for the 68.518 participants of the Norwegian Women and Cancer study using a food frequency questionnaire. The most common supplement used was cod liver oil, said the researchers, followed by multivitamin and mineral supplements.

After adjusting the data to account for smoking status, the age at which the participants were diagnosed, and the stage of the cancer, Skeie and his co-workers report that consumption of cod liver oil daily for a year prior to diagnosis was associated with a 23 per cent reduction in the risk of death in patients with solid tumours, and a reduction of 44 per cent in lung cancer patients.

Additionally, daily and occasional use of other dietary supplements was associated with 30 and 45 per cent reduction, respectively, in the risk of death among lung cancer patients.

“When use of cod liver oil and other dietary supplements were combined into one variable daily use of both cod liver oil and other dietary supplements was associated with improved survival in lung cancer patients,” added Skeie.

Before or after?

Commenting on their study design, the researchers noted: “If the most relevant period for supplementation is after diagnosis, it is likely that our results underestimate the effect of supplementation, as some of the patients most likely have initiated supplementation.

“On the other hand, if a certain level of the nutrients or long-term supplementation is required for an effect, dietary supplement use before diagnosis might be more relevant for the association with survival.

“And if dietary supplement use only is an indicator of a set of health behaviours or beliefs, prediagnosis use might be more important, as these characteristics probably are stronger in those who already take supplements before diagnosis, than in those who initiate use afterwards.”

The researchers called for more research to study the apparent benefits of supplement use for survival chances in people with solid tumours.

“In countries where dietary supplement use is common, analyses of survival in cancer patients, particularly lung cancer patients, should take dietary supplement use into account,” they concluded.

Source: International Journal of Cancer
Volume 125, Pages 1155-1160
"Cod liver oil, other dietary supplements and survival among cancer patients with solid tumours"
Authors: G. Skeie, T. Braaten, A. Hjartaker, M. Brustad, E. Lund

NutraIngredients-USA.com

資料來源：

http://www.nutraingredients-usa.com/Product-Categories/Antioxidants-carotenoids/Supplement-users-may-have-better-cancer-survival-Study/?utm_source=Newsletter_Product&utm_medium=email&utm_campaign=Newsletter%2BProduct